Filtration systems

PALL Efficient and reliable membrane air, gas and vent filtration are perfect for biopharmaceutical production to protect the quality of drug products. Sterilizing-grade air filters are used for biopharmaceutical products from contamination by microorganisms or particles during processes, this is done through gas venting from tanks or bioreactors, compressed gas filtration, and high-temperature or highly oxidizing situations. Non-sterilizing filters reduce bioburden for non-critical applications.

PALL bioburden reduction filters with Bio-Inert® grade NBL membrane are validated for bioburden control to acheive a typical titer reduction of > 7 LRV when challenged with B. diminuta. These filters have broad compatibilty for flexibility of use in multiple applications with low adsorptive properties that minimises binding of product and other active ingredients. Incorporating two layers of modified filter membrane exhibit broad liquid compatibility where the binding of any active ingredients must be kept to a minimum.

PALL Fluorodyne sterile filters are rated high capacity, low protein binding durable and compact design sterilizing grade filters. Incorporating a built-in prefiltration layer and validated to retain microbes at a challenge level of low membrane area. Both prefiltration and filtration layers provide high protein transmission to give the highest quality product. These filters come as cartridges and capsules which are replicable and suitable for medium to large scale production and are ideal for the sterile filtration of cell harvest material and challenging in...

Pall Mycoplasma Removal Filters are an encapsulated small Core filters designed for more area. The asymmetric built-in prefilter for highest dirt-holding capacity > 10 log A. The high flow rate of these filters guarantees low protein and preservative binding and low extractables. The filters are designed for autoclaving or SIP under wet or dry conditions.

PALL particulate filter cartridges are all-fluoropolymer cartridges which are ideal for bioburden reduction in agressive process fluids. The pleat technology for high flow rates, increased dirt holding capacity and long service life. The all-fluoropolymer construction provides excellent compatibility with agressive fluids. These filters can also be in situ steamed or autoclaved and the single open-ended (SOE) AB filter cartridge style features a high-area pleated modular element construction designed to fit in sanitary filter housings.

Pall Filter Integrity Test Systems are ideal component for maintaining efficient manufacturing rates and high quality products. It can perform water intrusion testing, forward flow testing and other indication testing. The fully automated test prep and cycle feature saves the operator time. Pall ensures reliable and reproducible test results while guaranteeing safety of digital records. Pall integrity testers allow up to four different cartridges or housings either hydrophobic or hydrophilic to be tested at once. This level of flexibility saves time and increasing...

the Pall Advanta range of housing has been designed and engineered specifically for the filtration of air and gases. The design complements the high-flow capacities of the Pall Emflon range of sterilizing gas filter cartridges to ensure reliable and cost efficient filtration. Where as the Pall IOL and IDL Single-round Housings are constructed of stainless steel and are designed for industrial and biopharmaceutical applications. Also, the Pall Advanta™ II ALI high-quality filter housings designed for critical liquid and gas filtration applications.