For human testicular tissue
GM501 Collagenase is composed of NaCl, KCl, KH2PO4, MgSO4.7H2O, NaHCO3, CaCl2.2H2O, D(+)-Glucose anhydrous, Na-Lactate (50 % solution), Na-Pyruvate, EDTA, Alanyl-Glutamine, water, non-essential and essential Amino Acids, HEPES, Phenolred. It has an activity of 1000 CDU/ml (Collagen Digestion Units). The Collagenase is obtained from culture filtrates of Clostridium histolyticum.
GM501 Collagenase is manufactured and tested according to the following specifications:
- pH (at 37°C): 7.20-7.70
- Osmolality (mOsm/kg): 270-310
- Sterility: sterile – SAL10-3 (Sterility Assurance Level)
- Sperm Survival test (%): ≥ 80 survival after exposure of density selected spermatozoa to the test medium
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