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Spray Drying & Encapsulation Solutions


Particle formation for lab scale

Buchi Spray Drying & Encapsulation Solutions

Spray Dryers

Mini Spray Dryer S-300

The next generation laboratory spray dryer

With the Mini Spray Dryer S-300, BUCHI solidifies its position as a global market leader for more than 40 years. The laboratory spray dryer combines outstanding product design with unique instrument capabilities to offer a superior user experience.

Evaporation capacity:
1.0 L / h H2O, higher for organic solvents
Final particle size:
1 - 60 μm
up to 70 %

Highest level of automation and flexibility

With the Mini Spray Dryer S-300 you can benefit from the highest possible automation levels to improve your process efficiency and free more time for your formulations.

- Safe handling of organic solvents
- Substantial time savings with Auto Mode
- Higher process regulation and reproducibility
- Maximal flexibility with remote control possibilities
- User-friendly operation with method programming

Improved spray drying performance

The Mini Spray Dryer S-300 allows you to achieve highly reproducible results, speed up the optimization of your formulation and simplify upscaling applications.

- Comprehensive reporting with a push of a button
- Improved sample protection
- Improved reproducibility through system design
- Full compatibility with previous spray dryers

Clever features that make all the difference

BUCHI focuses on perfecting every detail so you can easily handle the Mini Spray Dryer S-300 and improve your spray drying performance.

- Easy maintenance with new cyclone mounting
- Coated cyclone for increased yields
- More stability with ruby stone in the nozzle
- Higher flexibility thanks to second sample pump
- Vast expertise in Application Database

Mini Spray Dryer B-290

The Mini Spray Dryer B-290, based on more than 30 years of spray drying experience, is marked by outstanding efficiency and flexibility. See why thousands of R&D publications have relied on the proven performance of the industry-leading spray dryer.

Evaporation capacity: 1.0 L / h H2O, higher for organic solvents
Final particle size: 1 - 60 μm
Yield: up to 70 %


The proven performance of BUCHI mini spray dryer has helped convince countless researchers of the system's capabilities. The Mini Spray Dryer B-290, as the world's leading R&D solution for spray drying, is featured in more than a thousand publications and over 400 patents.


BUCHI spray drying solution is perfect for reproducible powder production on a lab scale. With the industry-favourite spray dryer, you can work with small sample amounts of as little as 5 g to save valuable material. BUCHI spray drying system is characterized by high yields (up to 70%) and low maintenance expenses for a cost-efficient performance. Fast drying processes (up to 1 L/h) enable you to quickly optimize formulations and save time.


You don't become the world's leading R&D solution in spray drying without offering intuitive handling, fast setup and easy maintenance. BUCHI Mini Spray Dryer B-290 offers you unmatched flexibility with adjustable particle sizes (2 to 25 microns) and with the possibility to scale up to pilot or industrial production. Thanks to the glass assembly design, you gain full visibility of the spray drying process, so you can make faster, better informed decisions during the procedure.

Nano Spray Dryer B-90 HP

With the Nano Spray Dryer B-90 HP, gently process the smallest sample amounts into submicron particles with minimal product loss. The user-friendly system improves productivity in areas where small particles make a big difference.

Evaporation capacity: 0.2 L / h H2O (higher for organic solvents)
Final particle size: 200 nm - 5 μm
Yield: up to 90%

Small particles

If you would like to produce small particles (0.2-5 µm) in a safe and controlled manner, then BUCHI Nano Spray Dryer B-90 HP fits your needs. With the Nano Srpay Dryer B-90 HP, you gain a larger surface contact area due to reduced particle size. The gentle process conditions help preserve molecular activity in your compounds of interest.

High yields

The piezzo driven spray head optimizes your productivity and makes your system easier to handle. If you are trying to improve product yields, BUCHI patented airflow systems for gentle solvent evaporation combined with an electrostatic particle collector can help you achieve higher recoveries. For most-efficienty use of your spray dryer, use the Auto-Stop mode to prevent the machine from running empty.

Small samples

BUCHI solution enables you to process very small volumes (<2 mL) of sample quickly and efficiently. Limit any product loss thanks to efficient particle recovery with BUCHI Nano Spray Dryer B-90 HP. Should you require any further support, you can easily access BUCHI vast application database to help improve your spray drying process.

Encapsulator B-390 / B-395

The Encapsulator B-390 / B-395 is a versatile system for encapsulation of active ingredients and materials for R&D purposes. From pharma to food samples, the adaptability of the device lets you obtain innovative microbeads and microcapsules.

Capsule type: matrix beads or core shell capsules
Final particle size: 150 μm - 4 mm
Productivity: 1 - 40 mL / min


The Encapsulator B-395 makes sterile encapsulation of cells, microorganisms and active ingredients possible. You can aseptically introduce and remove fluids and products to and from the reaction vessel. You can also readily integrate the encapsulation instrument in a GMP-compliant production process.

Increased efficiency

The low-impact encapsulation conditions made possible by the Encapsulator B-390 / B-395 can increase the efficiency and reproducibility of your encapsulation process. The encapsulation system offers you tight particle size distribution and high yields of a product with superior quality.

Flawless user experience

Enjoy a flawless user experience with the Encapsulator B-390 / B-395 thanks to intuitive operation and easy maintenace. The ability to directly see the droplet formation gives you comprehensive access to the process and enables you to quickly and confidently optimize your encapsulation. We offer extensive support, so you can easily adapt the system to your particular samples and needs. Rely on BUCHI established application database or talk to our certified application specialists to optimize and personalize your system performance.


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