Home » Products » Analytical Solutions » Pipettes & Liquid Handling » Mettler Toledo Multichannel Manual Pipettes
Comfortable, ergonomic pipette
Mettler Toledo’s Rainin XLS+ manual multichannel pipettes are engineered to deliver high-performance liquid handling for 96-well plate applications, combining mechanical precision with advanced ergonomics. These instruments feature a specialized manifold design that ensures balanced pressure and consistent aspiration across all 8 or 12 channels simultaneously.
Technically, the XLS+ utilizes high-quality internal components to minimize friction and ensure smooth plunger travel, which is critical for maintaining volumetric accuracy and reducing operator fatigue during repetitive manual tasks. The integration of the patented LiteTouch System (LTS) ensures that all tips seal perfectly with minimal force, providing the reliability and reproducibility required for complex biological and chemical assays.
Advanced Manifold Engineering for Uniform Aspiration
The technical excellence of the Rainin XLS+ multichannel pipette lies in its precision-engineered manifold. This component is designed to distribute air displacement equally across all 8 or 12 channels. By ensuring that the internal pressure is perfectly balanced, the instrument guarantees that every tip aspirates the exact same volume of liquid. This uniformity is essential for high-throughput screening and plate-based assays, where even minor variations between wells can lead to significant experimental errors and inconsistent data.
Patented LiteTouch System (LTS) Technology
A critical technical challenge in manual multichannel pipetting is achieving a reliable seal for all tips without excessive force. Mettler Toledo addresses this with the LiteTouch System (LTS). Unlike traditional conical nozzles, LTS utilizes a cylindrical nozzle with a thin sealing ring and a positive stop. This design ensures that each tip reaches the exact same depth and creates a perfect, leak-proof seal with minimal effort. This consistency across the entire head is vital for synchronized liquid delivery and significantly reduces tip ejection forces.
Precision Volume Adjustment and Locking Mechanism
The XLS+ is equipped with a high-resolution mechanical counter that allows for precise volume settings. To maintain technical integrity during operation, the pipette features a robust locking mechanism. This prevents the volume from drifting or being accidentally changed due to hand movement during repetitive pipetting cycles. The smooth-turning adjustment dial allows researchers to dial in target volumes with high repeatability, ensuring that the volumetric performance remains within strict tolerances throughout the entire procedure.
High-Performance Internal Piston Synchronicity
The internal mechanical assembly of the XLS+ is designed for absolute synchronicity. Each channel's piston is linked to a central drive mechanism that ensures simultaneous movement. Technically, this means that the velocity and displacement of each piston are identical, resulting in uniform aspiration and dispensing across the entire row or column of a microplate. The use of low-friction seals and high-quality materials ensures that this synchronicity is maintained over thousands of cycles without degradation in performance.
Ergonomic Design and Fatigue Mitigation
Manual multichannel pipetting is physically demanding, often leading to repetitive strain injuries. The XLS+ is technically optimized for ergonomics, featuring a lightweight chassis and a perfectly balanced center of gravity. The handle is contoured to fit comfortably in the hand, and the integrated finger hook allows for a relaxed grip. By reducing the force required for plunger movement and tip ejection, the XLS+ minimizes the physical load on the operator, allowing for high-accuracy performance even during long-duration plate-filling tasks.
Integrated RFID for Compliance and Management
To support laboratory management and regulatory compliance, every Rainin XLS+ multichannel pipette contains an embedded RFID (Radio Frequency Identification) chip. This chip stores the instrument's technical data, including serial number, calibration dates, and service history. When paired with an RFID reader and dedicated software, this allows for automated asset tracking and ensures that only properly maintained and calibrated pipettes are used in the lab. This feature is particularly important for maintaining GLP and GMP standards in regulated environments.
Chemical Resistance and Material Durability
The technical construction of the XLS+ involves the use of high-grade, chemically resistant materials. The external housing and internal components are selected to withstand exposure to a wide variety of laboratory reagents, including aggressive solvents and buffers. This material integrity ensures that the pipette remains accurate and functional over its lifespan, preventing mechanical failures or contamination issues. The surfaces are also designed for easy cleaning and decontamination, supporting use in sterile biological applications.
Reliability Across Diverse Volumetric Ranges
Mettler Toledo offers the XLS+ multichannel manual pipette in a variety of volume ranges to suit different laboratory needs. Whether performing micro-volume genomic work or larger volume reagent additions, the technical performance remains consistent. Each model is calibrated to meet rigorous ISO standards for accuracy and precision. The ability of the instrument to maintain low coefficients of variation (CV) across its entire volume range makes it a versatile and reliable tool for a broad spectrum of research and diagnostic workflows.
Read more about Mettler Toledo Multichannel Manual Pipettes