Electronic Multichannel Adjustable Spacer

Rapid Format Transfer Capability

The primary technical function of the E4 XLS Adjustable Spacer is the ability to change nozzle spacing to accommodate different labware. By turning the adjustment dial, the nozzles can expand or contract, allowing the tool to pick up samples from 9 mm spacing (standard 96-well plates) and expand up to 19 mm for tubes or larger well plates. This capability eliminates the need for single-channel transfers, technically reducing the number of steps required for plate-to-plate or tube-to-plate transfers and significantly increasing throughput in high-volume laboratories.

Microprocessor-Controlled Piston Movement

The internal mechanical operation of the E4 XLS is governed by a high-precision stepper motor. Technically, this motor drives the piston movement with extreme consistency, which is superior to manual sampling tools where human speed and force can cause variability. This ensures that every channel aspirates and dispenses the exact same volume simultaneously. The microprocessor monitors the motor's position to maintain accuracy even across complex protocols such as multi-dispensing or sequential dilutions.

User Interface and Intuitive Joystick Control

The E4 XLS features a high-resolution color display and a multi-directional joystick that simplifies navigation through various operational modes. Technically, the interface allows users to set volume, speed, and cycle counts with digital precision. The joystick allows for rapid menu selection, and the display provides real-time feedback on the tool's status, including the current volume setting and the number of steps remaining in a dispensing sequence. This digital interface reduces the cognitive load on the operator and prevents setting errors.

Patented LTS (LiteTouch System) Technology

Mettler Toledo utilizes the LiteTouch System (LTS) in the E4 XLS Adjustable Spacer to ensure a perfect, leak-proof seal across all channels with minimal force. Technically, the LTS design uses a small, thin sealing ring and a positive stop to prevent the tips from being jammed onto the nozzles. This results in incredibly low tip ejection forces, which is particularly critical in multichannel tools where ejecting 6 or 8 tips at once could otherwise cause significant hand and thumb strain.

Advanced Operational Modes for Diverse Applications

Beyond simple liquid transfer, the E4 XLS is equipped with multiple software modes including Multi-dispense, Titrate, and Manual mode. Technically, these modes use the electronic motor to automate complex liquid handling tasks. For instance, in Multi-dispense mode, the tool aspirates a large volume and delivers multiple smaller aliquots, calculating the required volume for each step automatically. This automation ensures that delicate procedures like titration are performed with a level of repeatability that manual tools cannot achieve.

RFID Tracking for Compliance and Asset Management

Each E4 XLS Adjustable Spacer is equipped with an integrated RFID chip. This chip stores the tool’s unique serial number, service dates, and calibration history. Technically, this allows laboratory managers to scan the tool using an RFID reader to instantly pull up its maintenance records. This feature is vital for labs operating under GLP or GMP regulations, as it ensures that only properly calibrated and maintained tools are used for critical research or production tasks.

Superior Ergonomics and Strain Reduction

The ergonomic design of the E4 XLS is engineered to minimize the risk of repetitive strain injuries (RSI). The tool is perfectly balanced and features a finger hook that allows for a relaxed grip. Because the piston movement is electronic, the force required to operate the trigger is negligible compared to manual tools. This technical focus on ergonomics ensures that the user can maintain high levels of accuracy and concentration during long periods of sample transfer without experiencing physical fatigue.

Long-Life Lithium-Ion Battery and Power Management

To support heavy laboratory usage, the E4 XLS is powered by a high-capacity lithium-ion battery. The power management system is technically optimized to provide hours of continuous use on a single charge. The battery does not suffer from "memory effect," meaning it can be charged at any time without losing capacity. The system also includes an auto-sleep mode that preserves power when the tool is not in use, and the charging stand ensures the tool is stored vertically to protect the internal electronic and mechanical components.

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