Microscopes & Optics

Nikon’s inverted microscopes are built for the most demanding IVF applications, offering exceptional optical clarity, modular expandability, and mechanical stability. Their broad field-of-view (up to 25 mm in ECLIPSE Ti2) enhances live-cell observation and high-throughput imaging, while robust construction supports micromanipulation tasks like ICSI without drift or focus loss

Nikon’s upright microscopes, including the ECLIPSE Ci-L plus and Ci-E series, are built to address the challenges of fatigue, inconsistent illumination, and complex workflows in IVF laboratories. Their ergonomic features—adjustable binocular tubes, extended eyepieces, and low stage height—help reduce musculoskeletal strain during prolonged embryo evaluation. Eco-illumination LED technology ensures uniform, bright lighting with a 60,000-hour lifespan, minimizing heat and maintenance while preserving specimen integrity. Features like Light Intensit...

Nikon’s polarizing microscopes—including the ECLIPSE Ci-POL and LV100N POL LED—are designed for revealing contrast in anisotropic and birefringent specimens, using high-quality CFI60 infinity optics, both diascopic and episcopic illumination, and exceptional stability. They feature uniform, low-heat LED or halogen lighting to minimize focus drift, ergonomic design for space efficiency, and user-friendly functions like a built-in capture button and 360° adjustable stages. These capabilities make them ideal for precise structural analyses&mdash...

Nikon stereo microscopes, such as the SMZ25 and SMZ18, provide advanced 3D visualization with wide zoom ranges and superior resolution, enabling embryologists and researchers to observe samples from macro to micro scale without losing clarity. These systems are designed to minimize eye fatigue with ergonomic features, while offering modular adaptability for fluorescence and digital imaging. By integrating high-NA objectives and widefield optics, they ensure accurate embryo handling, sample manipulation, and material inspection.

Nikon’s confocal and multiphoton microscopes are designed to overcome the fundamental challenges of high-resolution biological imaging. Confocal systems like the AX/AX R and A1 HD25 provide large field-of-view (up to 25 mm), fast acquisition, and precise optical sectioning for detailed 3D reconstructions. Multiphoton microscopes extend this capability deeper into living tissues, reducing phototoxicity and preserving embryo viability during long-term imaging. Together, these platforms enable researchers and IVF specialists to visualize fine subcellular struct...

Traditional optical microscopes are limited by the diffraction barrier, restricting resolution to around 200 nm and preventing visualization of critical subcellular structures. Nikon’s super-resolution platforms, such as N-SIM (Structured Illumination Microscopy) and N-STORM (Stochastic Optical Reconstruction Microscopy), break this barrier—achieving up to 20 nm resolution. This allows embryologists and researchers to observe subcellular organelles, protein interactions, and embryo ultrastructure with unprecedented clarity. For IVF labs, this means mor...

Total Internal Reflection Fluorescence (TIRF) and photo-stimulation microscopy represent advanced modalities that solve long-standing problems in live-cell and IVF imaging. TIRF enables visualization of events near the cell membrane—such as vesicle trafficking or fertilization dynamics—with unmatched signal-to-noise ratio. Nikon’s systems combine TIRF with super-resolution and confocal modules for multimodal imaging. Photo-stimulation adds the ability to manipulate cellular activity with light, enabling precise control of embryo development pathw...